01 - Pat shrimp dry with paper towels and season evenly with kosher salt and black pepper.
02 - Arrange three shallow bowls. In the first, combine flour, cornstarch, garlic powder, and smoked paprika. Beat eggs in the second bowl. Place panko breadcrumbs in the third bowl.
03 - Dredge each shrimp in the flour mixture, shaking off excess. Dip into beaten egg, then press firmly into panko to coat thoroughly.
04 - Pour 2 inches of vegetable oil into a deep skillet or Dutch oven. Heat to 350°F.
05 - Fry shrimp in batches for 2–3 minutes, turning once halfway through, until golden brown and crispy. Transfer to a paper towel-lined plate to drain.
06 - In a small saucepan over low heat, melt butter with honey, hot sauce, and red pepper flakes. Whisk until combined and just heated through.
07 - Toss fried shrimp with hot honey glaze until evenly coated. Serve immediately garnished with fresh chives or parsley and lemon wedges.